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Geetha Melangath
Geetha Melangath
Research Fellow at Mass. Eye and Ear, Harvard Medical School
Verified email at meei.harvard.edu
Title
Cited by
Cited by
Year
Ultraviolet A light induces DNA damage and estrogen-DNA adducts in Fuchs endothelial corneal dystrophy causing females to be more affected
C Liu, T Miyajima, G Melangath, T Miyai, S Vasanth, N Deshpande, ...
Proceedings of the National Academy of Sciences 117 (1), 573-583, 2020
852020
Activation of PINK1-parkin–mediated mitophagy degrades mitochondrial quality control proteins in Fuchs endothelial corneal dystrophy
T Miyai, S Vasanth, G Melangath, N Deshpande, V Kumar, AS Benischke, ...
The American Journal of Pathology 189 (10), 2061-2076, 2019
352019
Loss of NQO1 generates genotoxic estrogen-DNA adducts in Fuchs Endothelial Corneal Dystrophy
T Miyajima, G Melangath, S Zhu, N Deshpande, S Vasanth, B Mondal, ...
Free Radical Biology and Medicine 147, 69-79, 2020
202020
Functions for fission yeast splicing factors SpSlu7 and SpPrp18 in alternative splice-site choice and stress-specific regulated splicing
G Melangath, T Sen, R Kumar, P Bawa, S Srinivasan, U Vijayraghavan
PLoS One 12 (12), e0188159, 2017
112017
The fission yeast pre-mRNA-processing factor 18 (prp18+) has intron-specific splicing functions with links to G1-S cell cycle progression
N Vijaykrishna, G Melangath, R Kumar, P Khandelia, P Bawa, ...
Journal of Biological Chemistry 291 (53), 27387-27402, 2016
92016
Splicing functions and global dependency on fission yeast slu7 reveal diversity in spliceosome assembly
S Banerjee, P Khandelia, G Melangath, S Bashir, V Nagampalli, ...
Molecular and Cellular Biology 33 (16), 3125-3136, 2013
92013
Increased corneal endothelial cell migration in Fuchs endothelial corneal dystrophy: a live cell imaging study
SO Tone, A Wylegala, M Böhm, G Melangath, N Deshpande, ...
Ophthalmology Science 1 (1), 100006, 2021
62021
Dysregulation of DNA repair genes in Fuchs endothelial corneal dystrophy
S Ashraf, N Deshpande, S Vasanth, G Melangath, RJ Wong, Y Zhao, ...
Experimental Eye Research 231, 109499, 2023
22023
Defective DNA Repair in Fuchs endothelial corneal dystrophy
N Deshpande, G Melangath, S Vasanth, M Price, F Price, UV Jurkunas
Investigative Ophthalmology & Visual Science 62 (8), 838-838, 2021
12021
NQO1 downregulation generates genotoxic DNA adducts in in vitro FECD model
T Miyajima, S Vasanth, G Melangath, N Deshpande, Y Chen, M Zahid, ...
Investigative ophthalmology & visual science 60 (9), 2177-2177, 2019
12019
Immortalization of FuchsEndothelial Corneal Dystrophy (FECD) Corneal Endothelial Cells (CEnC) Retains TCF4 Repeat Expansion
SO Tone, G Melangath, N Deshpande, UV Jurkunas
Investigative ophthalmology & visual science 60 (9), 2174-2174, 2019
12019
Loss of NQO1 exacerbates female susceptibility to the development of Fuchs dystrophy in response to ultraviolet light.
V Kumar, N Deshpande, G Melangath, H Hui, S Zhu, U Jurkunas
Investigative Ophthalmology & Visual Science 61 (7), 1470-1470, 2020
2020
Deregulation of mitochondrial DNA repair genes in Fuchs Endothelial Corneal Dystrophy
G Melangath, S Vasanth, N Deshpande, V Kumar, M Price, F Price Jr, ...
Investigative Ophthalmology & Visual Science 61 (7), 1471-1471, 2020
2020
Altered DNA damage response in pathogenesis of Fuchs Endothelial Corneal Dystrophy
N Deshpande, G Melangath, S Vasanth, V Kumar, U Jurkunas
Investigative Ophthalmology & Visual Science 61 (7), 1473-1473, 2020
2020
Increased corneal endothelial cell migration in Fuchs endothelial corneal dystrophy, with or without TCF4 repeat expansion
SO Tone, A Wylegala, MS Boehm, G Melangath, U Jurkunas
Investigative Ophthalmology & Visual Science 61 (7), 1188-1188, 2020
2020
Increased mitochondrial DNA damage in females in the UV-A induced FECD model
G Melangath, C Liu, T Miyajima, S Vasanth, N Deshpande, T Miyai, ...
Investigative Ophthalmology & Visual Science 60 (9), 2178-2178, 2019
2019
Role of DNA damage repair in Fuchs Endothelial Corneal Dystrophy
N Deshpande, Y Chen, T Schmedt, S Vasanth, G Melangath, ...
Investigative Ophthalmology & Visual Science 60 (9), 2180-2180, 2019
2019
Understanding Functions for Fission Yeast Pre-mRNA Splicing Factors SpPrp18 and SpSlu7 in Constitutive and Alternative Splicing
G Melangath
2017
Global splicing functions of SpSlu7 reveal diversity in spliceosome assembly
G Melangath, S Banerjee, S Bashir, V Nagampalli, U Vijayraghavan
YEAST 30 (1), 68, 2013
2013
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EY Chew, MB Gorin, J Ahn, SO Tone, A Wylegala, M Böhm, G Melangath, ...
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