Bradley M Dickson
Bradley M Dickson
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Multivalent histone engagement by the linked tandem Tudor and PHD domains of UHRF1 is required for the epigenetic inheritance of DNA methylation
SB Rothbart, BM Dickson, MS Ong, K Krajewski, S Houliston, DB Kireev, ...
Genes and Development 27 (11), 1288-1298, 2013
An interactive database for the assessment of histone antibody specificity
SB Rothbart, BM Dickson, JR Raab, AT Grzybowski, K Krajewski, AH Guo, ...
Molecular cell 59 (3), 502-511, 2015
A cellular chemical probe targeting the chromodomains of Polycomb repressive complex 1
JI Stuckey, BM Dickson, N Cheng, Y Liu, JL Norris, SH Cholensky, ...
Nature chemical biology 12 (3), 180-187, 2016
Hemi-methylated DNA regulates DNA methylation inheritance through allosteric activation of H3 ubiquitylation by UHRF1
JS Harrison, EM Cornett, D Goldfarb, PA DaRosa, ZM Li, F Yan, ...
Elife 5, e17101, 2016
Examining the roles of H3K4 methylation states with systematically characterized antibodies
RN Shah, AT Grzybowski, EM Cornett, AL Johnstone, BM Dickson, ...
Molecular cell 72 (1), 162-177. e7, 2018
Free energy calculations: An efficient adaptive biasing potential method
BM Dickson, F Legoll, T Lelievre, G Stoltz, P Fleurat-Lessard
The Journal of Physical Chemistry B 114 (17), 5823-5830, 2010
Identification of a Fragment-like Small Molecule Ligand for the Methyl-lysine Binding Protein, 53BP1
et al MT Perfetti, BM Baughman, BM Dickson
ACS Chemical Biology, 2015
αC helix as a switch in the conformational transition of Src/CDK-like kinase domains
H Huang, R Zhao, BM Dickson, RD Skeel, CB Post
The Journal of Physical Chemistry B 116 (15), 4465-4475, 2012
The structural basis of the dominant negative phenotype of the Gαi1β1γ2 G203A/A326S heterotrimer
P Liu, M Jia, XE Zhou, PW De Waal, BM Dickson, B Liu, L Hou, Y Yin, ...
Acta Pharmacologica Sinica 37 (9), 1259-1272, 2016
Molecular mechanisms of fentanyl mediated β-arrestin biased signaling
PW De Waal, J Shi, E You, X Wang, K Melcher, Y Jiang, HE Xu, ...
PLoS computational biology 16 (4), e1007394, 2020
Structure–activity relationships and kinetic studies of peptidic antagonists of CBX chromodomains
JI Stuckey, C Simpson, JL Norris-Drouin, SH Cholensky, J Lee, R Pasca, ...
Journal of medicinal chemistry 59 (19), 8913-8923, 2016
Approaching a parameter-free metadynamics
BM Dickson
Physical Review E 84 (037701), 2011
Chromatin structure and its chemical modifications regulate the ubiquitin ligase substrate selectivity of UHRF1
RM Vaughan, BM Dickson, MF Whelihan, AL Johnstone, EM Cornett, ...
Proceedings of the National Academy of Sciences 115 (35), 8775-8780, 2018
Parallel replica dynamics with a heterogeneous distribution of barriers: Application to n-hexadecane pyrolysis
O Kum, BM Dickson, SJ Stuart, BP Uberuaga, AF Voter
The Journal of chemical physics 121 (20), 9808-9819, 2004
Unrestrained computation of free energy along a path
BM Dickson, H Huang, CB Post
The Journal of Physical Chemistry B 116 (36), 11046-11055, 2012
A functional proteomics platform to reveal the sequence determinants of lysine methyltransferase substrate selectivity
EM Cornett, BM Dickson, K Krajewski, N Spellmon, A Umstead, ...
Science advances 4 (11), eaav2623, 2018
Comparative biochemical analysis of UHRF proteins reveals molecular mechanisms that uncouple UHRF2 from DNA methylation maintenance
RM Vaughan, BM Dickson, EM Cornett, JS Harrison, B Kuhlman, ...
Nucleic acids research 46 (9), 4405-4416, 2018
The structure–activity relationships of L3MBTL3 inhibitors: flexibility of the dimer interface
MA Camerino, N Zhong, A Dong, BM Dickson, LI James, BM Baughman, ...
Medchemcomm 4 (11), 1501-1507, 2013
Pitfalls of choosing an order parameter for rare event calculations
BM Dickson, DE Makarov, G Henkelman
The Journal of chemical physics 131 (7), 2009
Quantitative characterization of bivalent probes for a dual bromodomain protein, transcription initiation factor TFIID subunit 1
JL Suh, B Watts, JI Stuckey, JL Norris-Drouin, SH Cholensky, BM Dickson, ...
Biochemistry 57 (14), 2140-2149, 2018
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