David Ochoa
David Ochoa
Platform Coordinator in OpenTargets (EMBL-EBI)
Verified email at - Homepage
Cited by
Cited by
The functional landscape of the human phosphoproteome
D Ochoa, AF Jarnuczak, C Viéitez, M Gehre, M Soucheray, A Mateus, ...
Nature biotechnology 38 (3), 365-373, 2020
Open Targets Genetics: systematic identification of trait-associated genes using large-scale genetics and functional genomics
M Ghoussaini, E Mountjoy, M Carmona, G Peat, EM Schmidt, A Hercules, ...
Nucleic acids research 49 (D1), D1311-D1320, 2021
Open Targets Platform: supporting systematic drug–target identification and prioritisation
D Ochoa, A Hercules, M Carmona, D Suveges, A Gonzalez-Uriarte, ...
Nucleic acids research 49 (D1), D1302-D1310, 2021
An atlas of human kinase regulation
D Ochoa, M Jonikas, RT Lawrence, B El Debs, J Selkrig, A Typas, J Villén, ...
Molecular systems biology 12 (12), 888, 2016
An open approach to systematically prioritize causal variants and genes at all published human GWAS trait-associated loci
E Mountjoy, EM Schmidt, M Carmona, J Schwartzentruber, G Peat, ...
Nature Genetics 53 (11), 1527-1533, 2021
Studying the co-evolution of protein families with the Mirrortree web server
D Ochoa, F Pazos
Bioinformatics 26 (10), 1370-1371, 2010
The PROTACtable genome
M Schneider, CJ Radoux, A Hercules, D Ochoa, I Dunham, LP Zalmas, ...
Nature Reviews Drug Discovery 20 (10), 789-797, 2021
Benchmarking substrate-based kinase activity inference using phosphoproteomic data
C Hernandez-Armenta, D Ochoa, E Gonçalves, J Saez-Rodriguez, ...
Bioinformatics 33 (12), 1845-1851, 2017
Epigenomic co-localization and co-evolution reveal a key role for 5hmC as a communication hub in the chromatin network of ESCs
D Juan, J Perner, EC de Santa Pau, S Marsili, D Ochoa, HR Chung, ...
Cell reports 14 (5), 1246-1257, 2016
Capturing variation impact on molecular interactions in the IMEx Consortium mutations data set
N Del-Toro, M Duesbury, M Koch, L Perfetto, A Shrivastava, D Ochoa, ...
Nature communications 10 (1), 1-14, 2019
Systematic analysis of transcriptional and post-transcriptional regulation of metabolism in yeast
E Gonçalves, Z Raguz Nakic, M Zampieri, O Wagih, D Ochoa, U Sauer, ...
PLoS computational biology 13 (1), e1005297, 2017
Conserved phosphorylation hotspots in eukaryotic protein domain families
MJ Strumillo, M Oplová, C Viéitez, D Ochoa, M Shahraz, BP Busby, ...
Nature communications 10 (1), 1-11, 2019
Practical aspects of protein co-evolution
D Ochoa, F Pazos
Frontiers in cell and developmental biology 2, 14, 2014
Detection of significant protein coevolution
D Ochoa, D Juan, A Valencia, F Pazos
Bioinformatics 31 (13), 2166-2173, 2015
Selection of organisms for the co-evolution-based study of protein interactions
D Herman, D Ochoa, D Juan, D Lopez, A Valencia, F Pazos
BMC bioinformatics 12 (1), 1-9, 2011
Multi-omics characterization of interaction-mediated control of human protein abundance levels
A Sousa, E Gonçalves, B Mirauta, D Ochoa, O Stegle, P Beltrao
Molecular & Cellular Proteomics 18 (8), S114-S125, 2019
High-throughput functional characterization of protein phosphorylation sites in yeast
C Viéitez, BP Busby, D Ochoa, A Mateus, D Memon, M Galardini, U Yildiz, ...
Nature biotechnology 40 (3), 382-390, 2022
Evolution, dynamics and dysregulation of kinase signalling
D Ochoa, D Bradley, P Beltrao
Current opinion in structural biology 48, 133-140, 2018
A proteome-wide genetic investigation identifies several SARS-CoV-2-exploited host targets of clinical relevance
M Anisul, J Shilts, J Schwartzentruber, J Hayhurst, A Buniello, ...
elife 10, e69719, 2021
Human genetics evidence supports two-thirds of the 2021 FDA-approved drugs.
D Ochoa, M Karim, M Ghoussaini, DG Hulcoop, EM McDonagh, I Dunham
Nature reviews. Drug discovery, 2022
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