Decreased consumption of branched-chain amino acids improves metabolic health L Fontana, NE Cummings, SIA Apelo, JC Neuman, I Kasza, BA Schmidt, ... Cell reports 16 (2), 520-530, 2016 | 402 | 2016 |
Alternative rapamycin treatment regimens mitigate the impact of rapamycin on glucose homeostasis and the immune system SI Arriola Apelo, JC Neuman, EL Baar, FA Syed, NE Cummings, HK Brar, ... Aging cell 15 (1), 28-38, 2016 | 178 | 2016 |
A novel rapamycin analog is highly selective for mTORC1 in vivo KH Schreiber, SI Arriola Apelo, D Yu, JA Brinkman, MC Velarde, FA Syed, ... Nature communications 10 (1), 3194, 2019 | 148 | 2019 |
Calorie-restriction-induced insulin sensitivity is mediated by adipose mTORC2 and not required for lifespan extension D Yu, JL Tomasiewicz, SE Yang, BR Miller, MH Wakai, DS Sherman, ... Cell reports 29 (1), 236-248. e3, 2019 | 77 | 2019 |
Molecular docking studies of anti-cancerous candidates in Hippophae rhamnoides and Hippophae salicifolia T Usha, SK Middha, AK Goyal, M Karthik, DA Manoj, S Faizan, P Goyal, ... Journal of biomedical research 28 (5), 406, 2014 | 62 | 2014 |
In silico–based combinatorial pharmacophore modelling and docking studies of GSK-3β and GK inhibitors of Hippophae SK Middha, AK Goyal, SA Faizan, N Sanghamitra, BC Basistha, T Usha Journal of biosciences 38, 805-814, 2013 | 34 | 2013 |
Design, synthesis, analysis, evaluation of cytotoxicity against MCF-7 breast cancer cells, 3D QSAR studies and EGFR, HER2 inhibition studies on Novel Biginelli 1, 4 … NL Naishima, S Faizan, RM Raju, ASVL Sruthi, NG Veena, GK Sharma, ... Journal of Molecular Structure 1277, 134848, 2023 | 14 | 2023 |
Design, parallel synthesis of Biginelli 1, 4-dihydropyrimidines using PTSA as a catalyst, evaluation of anticancer activity and structure activity relationships via 3D QSAR Studies S Faizan, BRP Kumar, NL Naishima, T Ashok, A Justin, MV Kumar, ... Bioorganic Chemistry 117, 105462, 2021 | 14 | 2021 |
A century-old one-pot multicomponent Biginelli reaction products still finds a niche in drug discoveries: Synthesis, mechanistic studies and diverse biological activities of … S Faizan, TF Roohi, RM Raju, S Yuvaraj, BRP Kumar Journal of Molecular Structure, 136020, 2023 | 9 | 2023 |
Novel derivatives of eugenol as potent anti-inflammatory agents via PPARγ agonism: Rational design, synthesis, analysis, PPARγ protein binding assay and computational studies NF Anjum, D Shanmugarajan, VK Shivaraju, S Faizan, NL Naishima, ... RSC advances 12 (26), 16966-16978, 2022 | 9 | 2022 |
Decreased consumption of branched-chain amino acids improves metabolic health. Cell Rep. 2016; 16 (2): 520–30 L Fontana, NE Cummings, SI Arriola Apelo, JC Neuman, I Kasza, ... | 9 | |
Novel derivatives of eugenol as a new class of PPARγ agonists in treating inflammation: design, synthesis, SAR analysis and in vitro anti-inflammatory activity NF Anjum, D Shanmugarajan, BR Prashantha Kumar, S Faizan, P Durai, ... Molecules 28 (9), 3899, 2023 | 6 | 2023 |
Rational design, molecular docking, dynamic simulation, synthesis, PPAR-γ competitive binding and transcription analysis of novel glitazones AP Kumar, S Mandal, P Prabitha, S Faizan, BRP Kumar, SP Dhanabal, ... Journal of Molecular Structure 1265, 133354, 2022 | 6 | 2022 |
A promising in silico protocol to develop novel PPARγ antagonists as potential anticancer agents: Design, synthesis and experimental validation via PPARγ protein activity and … Y Sivamani, D Shanmugarajan, TDA Kumar, S Faizan, B Channappa, ... Computational Biology and Chemistry 95, 107600, 2021 | 5 | 2021 |
Molecular dynamics articulated multilevel virtual screening protocol to discover novel dual PPAR α/γ agonists for anti-diabetic and metabolic applications S Mandal, S Faizan, NM Raghavendra, BRP Kumar Molecular Diversity 27 (6), 2605-2631, 2023 | 3 | 2023 |
A multifaceted approach for the development of novel Hantzsch 1, 4-dihydropyridines as anticancer agents: Rational design, parallel synthesis, analysis, cytotoxicity and EGFR … A Sruthi, S Faizan, H Vikram, NG Veena, A Susil, H Harindranath, ... Results in Chemistry, 101413, 2024 | 1 | 2024 |
Beyond Glucose: The Dual Assault of Oxidative and ER Stress in Diabetic Disorders TF Roohi, S Faizan, ZA Parray, MDAI Baig, S Mehdi, N Kinattingal, ... High Blood Pressure & Cardiovascular Prevention 30 (6), 513-531, 2023 | 1 | 2023 |
Activation of PIEZO1 Evokes Calcium Flux and Promotes Human Airway Smooth Muscle Cell Relaxation D Mak, V Nagaraj, NR Dahiya, F Syed, H Son, JM Lee, DY Jung, S Yang, ... D30. A NARROW ROAD TO AIRWAY HYPERRESPONSIVENESS, A7200-A7200, 2024 | | 2024 |
N-Substituted dihydropyridines as promising EGFR tyrosine kinase inhibitors against breast cancer: Design, synthesis, biological evaluation, docking, and molecular dynamics … S Faizan, U Hani, N Haider, V Vadivel, BRP Kumar Results in Chemistry, 101502, 2024 | | 2024 |
Quinone scaffolds as potential therapeutic anticancer agents: Chemistry, mechanism of Actions, Structure-Activity relationships and future perspectives S Faizan, MMA Mohsen, C Amarakanth, A Justin, RR Rahangdale, ... Results in Chemistry, 101432, 2024 | | 2024 |