TGF-β signalling from cell membrane to nucleus through SMAD proteins CH Heldin, K Miyazono, P Ten Dijke Nature 390 (6659), 465-471, 1997 | 5026 | 1997 |
Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways H Ichijo, E Nishida, K Irie, P Dijke, M Saitoh, T Moriguchi, M Takagi, ... Science 275 (5296), 90-94, 1997 | 2750 | 1997 |
Identification of Smad7, a TGFβ-inducible antagonist of TGF-β signalling A Nakao, M Afrakhte, A Morn, T Nakayama, JL Christian, R Heuchel, ... Nature 389 (6651), 631-635, 1997 | 2318 | 1997 |
Direct binding of Smad3 and Smad4 to critical TGFβ-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene S Dennler, S Itoh, D Vivien, P ten Dijke, S Huet, JM Gauthier The EMBO journal 17 (11), 3091-3100, 1998 | 2137 | 1998 |
New insights into TGF-β–Smad signalling P ten Dijke, CS Hill Trends in biochemical sciences 29 (5), 265-273, 2004 | 1622 | 2004 |
Balancing the activation state of the endothelium via two distinct TGF-β type I receptors MJ Goumans, G Valdimarsdottir, S Itoh, A Rosendahl, P Sideras, ... The EMBO journal 21 (7), 1743-1753, 2002 | 1415 | 2002 |
TGF-β receptor-mediated signalling through Smad2, Smad3 and Smad4 A Nakao, T Imamura, S Souchelnytskyi, M Kawabata, A Ishisaki, E Oeda, ... The EMBO journal 16 (17), 5353-5362, 1997 | 1307 | 1997 |
Specificity, diversity, and regulation in TGF‐β superfamily signaling E Piek, CH HELDIN, PTEN DIJKE The FASEB Journal 13 (15), 2105-2124, 1999 | 1197 | 1999 |
Activin receptor-like kinase 1 modulates transforming growth factor-β1 signaling in the regulation of angiogenesis SP Oh, T Seki, KA Goss, T Imamura, Y Yi, PK Donahoe, L Li, K Miyazono, ... Proceedings of the National Academy of Sciences 97 (6), 2626-2631, 2000 | 1064 | 2000 |
Sclerostin is an osteocyte-expressed negative regulator of bone formation, but not a classical BMP antagonist RL Van Bezooijen, BAJ Roelen, A Visser, L Van Der Wee-pals, E De Wilt, ... The Journal of experimental medicine 199 (6), 805-814, 2004 | 1031 | 2004 |
TGF-β signaling by Smad proteins K Miyazono Cytokine & growth factor reviews 11 (1-2), 15-22, 2000 | 1028 | 2000 |
Identification and functional characterization of distinct critically important bone morphogenetic protein-specific response elements in the Id1 promoter O Korchynskyi, P Ten Dijke Journal of Biological Chemistry 277 (7), 4883-4891, 2002 | 980 | 2002 |
Cloning of a TGFβ type I receptor that forms a heteromeric complex with the TGFβ type II receptor P Franzen, P ten Dijke, H Ichijo, H Yamashita, P Schulz, CH Heldin, ... Cell 75 (4), 681-692, 1993 | 975 | 1993 |
Extracellular control of TGFβ signalling in vascular development and disease P Ten Dijke, HM Arthur Nature reviews Molecular cell biology 8 (11), 857-869, 2007 | 971 | 2007 |
Identification of type I receptors for osteogenic protein-1 and bone morphogenetic protein-4. P Ten Dijke, H Yamashita, TK Sampath, AH Reddi, M Estevez, DL Riddle, ... Journal of Biological Chemistry 269 (25), 16985-16988, 1994 | 904 | 1994 |
Transforming growth factor-β1 to the bone K Janssens, P Ten Dijke, S Janssens, W Van Hul Endocrine reviews 26 (6), 743-774, 2005 | 879 | 2005 |
Signaling of transforming growth factor‐β family members through Smad proteins S Itoh, F Itoh, MJ Goumans, P ten Dijke European Journal of Biochemistry 267 (24), 6954-6967, 2000 | 859 | 2000 |
Activin receptor-like kinase (ALK) 1 is an antagonistic mediator of lateral TGFβ/ALK5 signaling MJ Goumans, G Valdimarsdottir, S Itoh, F Lebrin, J Larsson, C Mummery, ... Molecular cell 12 (4), 817-828, 2003 | 858 | 2003 |
Endoglin promotes endothelial cell proliferation and TGF‐β/ALK1 signal transduction F Lebrin, MJ Goumans, L Jonker, RLC Carvalho, G Valdimarsdottir, ... The EMBO journal 23 (20), 4018-4028, 2004 | 814 | 2004 |
Apoptosis in podocytes induced by TGF-β and Smad7 M Schiffer, M Bitzer, ISD Roberts, JB Kopp, P ten Dijke, P Mundel, ... The Journal of clinical investigation 108 (6), 807-816, 2001 | 800 | 2001 |