Elizabeth Jaffee
Elizabeth Jaffee
Johns Hopkins University School of Medicine
Adresă de e-mail confirmată pe jhmi.edu - Pagina de pornire
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Core signaling pathways in human pancreatic cancers revealed by global genomic analyses
S Jones, X Zhang, DW Parsons, JCH Lin, RJ Leary, P Angenendt, ...
science 321 (5897), 1801-1806, 2008
Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor …
G Dranoff, E Jaffee, A Lazenby, P Golumbek, H Levitsky, K Brose, ...
Proceedings of the National Academy of Sciences 90 (8), 3539-3543, 1993
Role of bone marrow-derived cells in presenting MHC class I-restricted tumor antigens
AY Huang, P Golumbek, M Ahmadzadeh, E Jaffee, D Pardoll, H Levitsky
Science 264 (5161), 961-965, 1994
Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene
S Jones, RH Hruban, M Kamiyama, M Borges, X Zhang, DW Parsons, ...
Science 324 (5924), 217-217, 2009
Mechanisms of immune evasion by tumors
CG Drake, E Jaffee, DM Pardoll
Advances in immunology 90, 51-81, 2006
Mesothelin is overexpressed in the vast majority of ductal adenocarcinomas of the pancreas identification of a new pancreatic cancer marker by Serial Analysis of Gene …
P Argani, C Iacobuzio-Donahue, B Ryu, C Rosty, M Goggins, RE Wilentz, ...
Clinical Cancer Research 7 (12), 3862-3868, 2001
Novel allogeneic granulocyte-macrophage colony-stimulating factor–secreting tumor vaccine for pancreatic cancer: a phase I trial of safety and immune activation
EM Jaffee, RH Hruban, B Biedrzycki, D Laheru, K Schepers, PR Sauter, ...
Journal of Clinical Oncology 19 (1), 145-156, 2001
Compromised HOXA5 function can limit p53 expression in human breast tumours
V Raman, SA Martensen, D Reisman, E Evron, WF Odenwald, E Jaffee, ...
Nature 405 (6789), 974-978, 2000
Safety and survival with GVAX pancreas prime and Listeria monocytogenes–expressing mesothelin (CRS-207) boost vaccines for metastatic pancreatic cancer
DT Le, A Wang-Gillam, V Picozzi, TF Greten, T Crocenzi, G Springett, ...
Journal of Clinical Oncology 33 (12), 1325-1333, 2015
Evaluation of ipilimumab in combination with allogeneic pancreatic tumor cells transfected with a GM-CSF gene in previously treated pancreatic cancer.
DT Le, E Lutz, JN Uram, EA Sugar, B Onners, S Solt, L Zheng, LA Diaz Jr, ...
Journal of immunotherapy (Hagerstown, Md.: 1997) 36 (7), 382-389, 2013
Exploration of global gene expression patterns in pancreatic adenocarcinoma using cDNA microarrays
CA Iacobuzio-Donahue, A Maitra, M Olsen, AW Lowe, NT Van Heek, ...
The American journal of pathology 162 (4), 1151-1162, 2003
Cyclophosphamide, doxorubicin, and paclitaxel enhance the antitumor immune response of granulocyte/macrophage-colony stimulating factor-secreting whole-cell vaccines in HER-2 …
JPH Machiels, RT Reilly, LA Emens, AM Ercolini, RY Lei, D Weintraub, ...
Cancer research 61 (9), 3689-3697, 2001
Bioactivity of autologous irradiated renal cell carcinoma vaccines generated by ex vivo granulocyte-macrophage colony-stimulating factor gene transfer
JW Simons, EM Jaffee, CE Weber, HI Levitsky, WG Nelson, MA Carducci, ...
Cancer research 57 (8), 1537-1546, 1997
Immunotherapy converts nonimmunogenic pancreatic tumors into immunogenic foci of immune regulation
ER Lutz, AA Wu, E Bigelow, R Sharma, G Mo, K Soares, S Solt, A Dorman, ...
Cancer immunology research 2 (7), 616-631, 2014
The immunodominant major histocompatibility complex class I-restricted antigen of a murine colon tumor derives from an endogenous retroviral gene product
AY Huang, PH Gulden, AS Woods, MC Thomas, CD Tong, W Wang, ...
Proceedings of the National Academy of Sciences 93 (18), 9730-9735, 1996
Recruitment of latent pools of high-avidity CD8+ T cells to the antitumor immune response
AM Ercolini, BH Ladle, EA Manning, LW Pfannenstiel, TD Armstrong, ...
The Journal of experimental medicine 201 (10), 1591-1602, 2005
The determinants of tumour immunogenicity
T Blankenstein, PG Coulie, E Gilboa, EM Jaffee
Nature Reviews Cancer 12 (4), 307-313, 2012
PD-1/PD-L1 blockade together with vaccine therapy facilitates effector T-cell infiltration into pancreatic tumors
KC Soares, AA Rucki, AA Wu, K Olino, Q Xiao, Y Chai, A Wamwea, ...
Journal of Immunotherapy 38 (1), 1-11, 2015
A lethally irradiated allogeneic granulocyte-macrophage colony stimulating factor-secreting tumor vaccine for pancreatic adenocarcinoma: a phase II trial of safety, efficacy …
E Lutz, CJ Yeo, KD Lillemoe, B Biedrzycki, B Kobrin, J Herman, E Sugar, ...
Annals of surgery 253 (2), 328, 2011
SMAD4 gene mutations are associated with poor prognosis in pancreatic cancer
A Blackford, OK Serrano, CL Wolfgang, G Parmigiani, S Jones, X Zhang, ...
Clinical Cancer Research 15 (14), 4674-4679, 2009
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