Biological insights from 108 schizophrenia-associated genetic loci C Pantelis, GN Papadimitriou, S Papiol, E Parkhomenko, MT Pato, ... Nature 511 (7510), 421-427, 2014 | 7578 | 2014 |
Common polygenic variation contributes to risk of schizophrenia and bipolar disorder International Schizophrenia Consortium Manuscript preparation Purcell Shaun ... Nature 460 (7256), 748-752, 2009 | 5307 | 2009 |
10 years of GWAS discovery: biology, function, and translation PM Visscher, NR Wray, Q Zhang, P Sklar, MI McCarthy, MA Brown, ... The American Journal of Human Genetics 101 (1), 5-22, 2017 | 3637 | 2017 |
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression NR Wray, S Ripke, M Mattheisen, M Trzaskowski, EM Byrne, A Abdellaoui, ... Nature genetics 50 (5), 668-681, 2018 | 2739 | 2018 |
Heritability in the genomics era—concepts and misconceptions PM Visscher, WG Hill, NR Wray Nature reviews genetics 9 (4), 255-266, 2008 | 2445 | 2008 |
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs B Devlin, JR Kelsoe, P Sklar, MJ Daly, MC O'Donovan, N Craddock, ... Nature genetics 45 (9), 984-994, 2013 | 2387 | 2013 |
Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets Z Zhu, F Zhang, H Hu, A Bakshi, MR Robinson, JE Powell, ... Nature genetics 48 (5), 481-487, 2016 | 2171 | 2016 |
Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions DM Howard, MJ Adams, TK Clarke, JD Hafferty, J Gibson, M Shirali, ... Nature neuroscience 22 (3), 343-352, 2019 | 2094 | 2019 |
Genome-wide association analysis identifies 13 new risk loci for schizophrenia S Ripke, C O'dushlaine, K Chambert, JL Moran, AK Kähler, S Akterin, ... Nature genetics 45 (10), 1150-1159, 2013 | 1776 | 2013 |
Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies MA Nalls, C Blauwendraat, CL Vallerga, K Heilbron, S Bandres-Ciga, ... The Lancet Neurology 18 (12), 1091-1102, 2019 | 1764 | 2019 |
Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection AF Pardiñas, P Holmans, AJ Pocklington, V Escott-Price, S Ripke, ... Nature genetics 50 (3), 381-389, 2018 | 1575 | 2018 |
Mapping genomic loci implicates genes and synaptic biology in schizophrenia V Trubetskoy, AF Pardiñas, T Qi, G Panagiotaropoulou, S Awasthi, ... Nature 604 (7906), 502-508, 2022 | 1507 | 2022 |
Genome-wide association study identifies 30 loci associated with bipolar disorder EA Stahl, G Breen, AJ Forstner, A McQuillin, S Ripke, V Trubetskoy, ... Nature genetics 51 (5), 793-803, 2019 | 1462 | 2019 |
Analysis of shared heritability in common disorders of the brain Brainstorm Consortium, V Anttila, B Bulik-Sullivan, HK Finucane, ... Science 360 (6395), eaap8757, 2018 | 1425 | 2018 |
Modeling linkage disequilibrium increases accuracy of polygenic risk scores BJ Vilhjálmsson, J Yang, HK Finucane, A Gusev, S Lindström, S Ripke, ... The american journal of human genetics 97 (4), 576-592, 2015 | 1400 | 2015 |
A mega-analysis of genome-wide association studies for major depressive disorder Major Depressive Disorder Working Group of the Psychiatric GWAS Consortium Molecular psychiatry 18 (4), 2013 | 1281 | 2013 |
Estimating missing heritability for disease from genome-wide association studies SH Lee, NR Wray, ME Goddard, PM Visscher The American Journal of Human Genetics 88 (3), 294-305, 2011 | 1222 | 2011 |
DNA methylation age of blood predicts all-cause mortality in later life RE Marioni, S Shah, AF McRae, BH Chen, E Colicino, SE Harris, J Gibson, ... Genome biology 16, 1-12, 2015 | 1163 | 2015 |
Genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders PH Lee, V Anttila, H Won, YCA Feng, J Rosenthal, Z Zhu, EM Tucker-Drob, ... Cell 179 (7), 1469-1482. e11, 2019 | 1128 | 2019 |
DNA methylation-based measures of biological age: meta-analysis predicting time to death BH Chen, RE Marioni, E Colicino, MJ Peters, CK Ward-Caviness, PC Tsai, ... Aging (Albany NY) 8 (9), 1844, 2016 | 1007 | 2016 |