Stephen Taylor
Stephen Taylor
Leech Professor of Pharmacology & Head of Division for Cancer Sciences, University of Manchester, UK
Verified email at - Homepage
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Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores
C Ditchfield, VL Johnson, A Tighe, R Ellston, C Haworth, T Johnson, ...
The Journal of cell biology 161 (2), 267-280, 2003
Cancer cells display profound intra-and interline variation following prolonged exposure to antimitotic drugs
KE Gascoigne, SS Taylor
Cancer cell 14 (2), 111-122, 2008
The spindle assembly checkpoint
P Lara-Gonzalez, FG Westhorpe, SS Taylor
Current biology 22 (22), R966-R980, 2012
Aurora-kinase inhibitors as anticancer agents
N Keen, S Taylor
Nature Reviews Cancer 4 (12), 927-936, 2004
Polo-like kinase-1 is activated by aurora A to promote checkpoint recovery
L Macůrek, A Lindqvist, D Lim, MA Lampson, R Klompmaker, R Freire, ...
Nature 455 (7209), 119-123, 2008
Kinetochore localization of murine Bub1 is required for normal mitotic timing and checkpoint response to spindle damage
SS Taylor, F McKeon
Cell 89 (5), 727-735, 1997
The human homologue of Bub3 is required for kinetochore localization of Bub1 and a Mad3/Bub1-related protein kinase
SS Taylor, E Ha, F McKeon
The Journal of cell biology 142 (1), 1-11, 1998
Dissecting the role of MPS1 in chromosome biorientation and the spindle checkpoint through the small molecule inhibitor reversine
S Santaguida, A Tighe, AM D'Alise, SS Taylor, A Musacchio
Journal of Cell Biology 190 (1), 73-87, 2010
How do anti-mitotic drugs kill cancer cells?
KE Gascoigne, SS Taylor
Journal of cell science 122 (15), 2579-2585, 2009
Bub1 is required for kinetochore localization of BubR1, Cenp-E, Cenp-F and Mad2, and chromosome congression
VL Johnson, MIF Scott, SV Holt, D Hussein, SS Taylor
Journal of cell science 117 (8), 1577-1589, 2004
The kinase haspin is required for mitotic histone H3 Thr 3 phosphorylation and normal metaphase chromosome alignment
J Dai, S Sultan, SS Taylor, JMG Higgins
Genes & development 19 (4), 472-488, 2005
Sustained Mps1 activity is required in mitosis to recruit O-Mad2 to the Mad1–C-Mad2 core complex
L Hewitt, A Tighe, S Santaguida, AM White, CD Jones, A Musacchio, ...
Journal of Cell Biology 190 (1), 25-34, 2010
Validating Aurora B as an anti-cancer drug target
F Girdler, KE Gascoigne, PA Eyers, S Hartmuth, C Crafter, KM Foote, ...
Journal of cell science 119 (17), 3664-3675, 2006
Recognizing and exploiting differences between RNAi and small-molecule inhibitors
WA Weiss, SS Taylor, KM Shokat
Nature chemical biology 3 (12), 739-744, 2007
Kinetochore localisation and phosphorylation of the mitotic checkpoint components Bub1 and BubR1 are differentially regulated by spindle events in human cells
SS Taylor, D Hussein, Y Wang, S Elderkin, CJ Morrow
Journal of cell science 114 (24), 4385-4395, 2001
Truncating APC mutations have dominant effects on proliferation, spindle checkpoint control, survival and chromosome stability
A Tighe, VL Johnson, SS Taylor
Journal of cell science 117 (26), 6339-6353, 2004
A visual screen of a GFP-fusion library identifies a new type of nuclear envelope membrane protein
MM Rolls, PA Stein, SS Taylor, E Ha, F McKeon, TA Rapoport
The Journal of cell biology 146 (1), 29-44, 1999
Regulation of APC/C activity in oocytes by a Bub1-dependent spindle assembly checkpoint
BE McGuinness, M Anger, A Kouznetsova, AM Gil-Bernabé, W Helmhart, ...
Current Biology 19 (5), 369-380, 2009
Bub1 and aurora B cooperate to maintain BubR1-mediated inhibition of APC/CCdc20
CJ Morrow, A Tighe, VL Johnson, MIF Scott, C Ditchfield, SS Taylor
Journal of cell science 118 (16), 3639-3652, 2005
Mps1 kinase activity restrains anaphase during an unperturbed mitosis and targets Mad2 to kinetochores
A Tighe, O Staples, S Taylor
The Journal of cell biology 181 (6), 893-901, 2008
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