| Silencing microRNA-134 produces neuroprotective and prolonged seizure-suppressive effects EM Jimenez-Mateos, T Engel, P Merino-Serrais, RC McKiernan, ... Nature medicine 18 (7), 1087-1094, 2012 | 504 | 2012 |
| Glycogen synthase kinase‐3 inhibition is integral to long‐term potentiation C Hooper, V Markevich, F Plattner, R Killick, E Schofield, T Engel, ... European journal of Neuroscience 25 (1), 81-86, 2007 | 407 | 2007 |
| Full reversal of Alzheimer's disease-like phenotype in a mouse model with conditional overexpression of glycogen synthase kinase-3 T Engel, F Hernández, J Avila, JJ Lucas Journal of Neuroscience 26 (19), 5083-5090, 2006 | 315 | 2006 |
| Chronic lithium administration to FTDP‐17 tau and GSK‐3β overexpressing mice prevents tau hyperphosphorylation and neurofibrillary tangle formation, but pre‐formed … T Engel, P Goñi‐Oliver, JJ Lucas, J Avila, F Hernández Journal of neurochemistry 99 (6), 1445-1455, 2006 | 273 | 2006 |
| miRNA Expression profile after status epilepticus and hippocampal neuroprotection by targeting miR-132 EM Jimenez-Mateos, I Bray, A Sanz-Rodriguez, T Engel, RC McKiernan, ... The American journal of pathology 179 (5), 2519-2532, 2011 | 231 | 2011 |
| Seizure suppression and neuroprotection by targeting the purinergic P2X7 receptor during status epilepticus in mice T Engel, R Gomez‐Villafuertes, K Tanaka, G Mesuret, A Sanz‐Rodriguez, ... The FASEB journal 26 (4), 1616-1628, 2012 | 220 | 2012 |
| Re-evaluation of neuronal P2X7 expression using novel mouse models and a P2X7-specific nanobody K Kaczmarek-Hajek, J Zhang, R Kopp, A Grosche, B Rissiek, A Saul, ... Elife 7, e36217, 2018 | 164 | 2018 |
| MicroRNAs in neurodegenerative diseases S Quinlan, A Kenny, M Medina, T Engel, EM Jimenez-Mateos International review of cell and molecular biology 334, 309-343, 2017 | 164 | 2017 |
| Unilateral hippocampal CA3-predominant damage and short latency epileptogenesis after intra-amygdala microinjection of kainic acid in mice G Mouri, E Jimenez-Mateos, T Engel, M Dunleavy, S Hatazaki, A Paucard, ... Brain research 1213, 140-151, 2008 | 163 | 2008 |
| Increased neocortical expression of the P 2X7 receptor after status epilepticus and anticonvulsant effect of P 2X7 receptor antagonist A‐438079 A Jimenez‐Pacheco, G Mesuret, A Sanz‐Rodriguez, K Tanaka, ... Epilepsia 54 (9), 1551-1561, 2013 | 160 | 2013 |
| Transient P2X7 receptor antagonism produces lasting reductions in spontaneous seizures and gliosis in experimental temporal lobe epilepsy A Jimenez-Pacheco, M Diaz-Hernandez, M Arribas-Blázquez, ... Journal of Neuroscience 36 (22), 5920-5932, 2016 | 148 | 2016 |
| Apoptosis, Bcl-2 family proteins and caspases: the ABCs of seizure-damage and epileptogenesis? T Engel, DC Henshall International journal of physiology, pathophysiology and pharmacology 1 (2), 97, 2009 | 145 | 2009 |
| Cooexpression of FTDP-17 tau and GSK-3β in transgenic mice induce tau polymerization and neurodegeneration T Engel, JJ Lucas, P Gómez-Ramos, MA Moran, J Ávila, F Hernández Neurobiology of aging 27 (9), 1258-1268, 2006 | 142 | 2006 |
| Reduced mature microRNA levels in association with dicer loss in human temporal lobe epilepsy with hippocampal sclerosis RC McKiernan, EM Jimenez-Mateos, I Bray, T Engel, GP Brennan, T Sano, ... PloS one 7 (5), e35921, 2012 | 137 | 2012 |
| Antagomirs targeting microRNA-134 increase hippocampal pyramidal neuron spine volume in vivo and protect against pilocarpine-induced status epilepticus EM Jimenez-Mateos, T Engel, P Merino-Serrais, I Fernaud-Espinosa, ... Brain Structure and Function 220, 2387-2399, 2015 | 116 | 2015 |
| microRNA targeting of the P2X7 purinoceptor opposes a contralateral epileptogenic focus in the hippocampus EM Jimenez-Mateos, M Arribas-Blazquez, A Sanz-Rodriguez, ... Scientific reports 5 (1), 17486, 2015 | 107 | 2015 |
| The ATP-gated P2X7 receptor as a target for the treatment of drug-resistant epilepsy E Beamer, W Fischer, T Engel Frontiers in Neuroscience 11, 241631, 2017 | 99 | 2017 |
| CHOP regulates the p53–MDM2 axis and is required for neuronal survival after seizures T Engel, A Sanz-Rodgriguez, EM Jimenez-Mateos, CG Concannon, ... Brain 136 (2), 577-592, 2013 | 97 | 2013 |
| ATPergic signalling during seizures and epilepsy T Engel, M Alves, C Sheedy, DC Henshall Neuropharmacology 104, 140-153, 2016 | 95 | 2016 |
| Proteins and microRNAs are differentially expressed in tear fluid from patients with Alzheimer’s disease A Kenny, EM Jimenez-Mateos, MA Zea-Sevilla, A Rábano, ... Scientific reports 9 (1), 15437, 2019 | 88 | 2019 |
