| Cryo-EM structure of the activated GLP-1 receptor in complex with a G protein Y Zhang, B Sun, D Feng, H Hu, M Chu, Q Qu, JT Tarrasch, S Li, ... Nature 546 (7657), 248-253, 2017 | 530 | 2017 |
| Structural insights into the activation of metabotropic glutamate receptors A Koehl, H Hu, D Feng, B Sun, Y Zhang, MJ Robertson, M Chu, ... Nature 566 (7742), 79-84, 2019 | 268 | 2019 |
| Structural basis of Wnt signaling inhibition by Dickkopf binding to LRP5/6 VE Ahn, MLH Chu, HJ Choi, D Tran, A Abo, WI Weis Developmental cell 21 (5), 862-873, 2011 | 199 | 2011 |
| Structural basis of GSK-3 inhibition by N-terminal phosphorylation and by the Wnt receptor LRP6 JL Stamos, MLH Chu, MD Enos, N Shah, WI Weis Elife 3, e01998, 2014 | 187 | 2014 |
| Crystal structure of the adenosine A2A receptor bound to an antagonist reveals a potential allosteric pocket B Sun, P Bachhawat, MLH Chu, M Wood, T Ceska, ZA Sands, J Mercier, ... Proceedings of the National Academy of Sciences 114 (8), 2066-2071, 2017 | 138 | 2017 |
| Drug-resistant aurora A mutants for cellular target validation of the small molecule kinase inhibitors MLN8054 and MLN8237 DA Sloane, MZ Trikic, MLH Chu, MBAC Lamers, CS Mason, I Mueller, ... ACS chemical biology 5 (6), 563-576, 2010 | 122 | 2010 |
| Structural studies of Wnts and identification of an LRP6 binding site MLH Chu, VE Ahn, HJ Choi, DL Daniels, R Nusse, WI Weis Structure 21 (7), 1235-1242, 2013 | 84 | 2013 |
| Discovery and exploitation of inhibitor-resistant aurora and polo kinase mutants for the analysis of mitotic networks PJ Scutt, MLH Chu, DA Sloane, M Cherry, CR Bignell, DH Williams, ... Journal of biological chemistry 284 (23), 15880-15893, 2009 | 80 | 2009 |
| Crystal structure of the catalytic domain of the mitotic checkpoint kinase Mps1 in complex with SP600125 MLH Chu, LMG Chavas, KT Douglas, PA Eyers, L Tabernero Journal of biological chemistry 283 (31), 21495-21500, 2008 | 65 | 2008 |
| Phosphoregulation of human Mps1 kinase RK Tyler, MLH Chu, H Johnson, EA McKenzie, SJ Gaskell, PA Eyers Biochemical Journal 417 (1), 173-184, 2009 | 62 | 2009 |
| Crystal structure of dopamine D1 receptor in complex with G protein and a non-catechol agonist B Sun, D Feng, MLH Chu, I Fish, S Lovera, ZA Sands, S Kelm, A Valade, ... Nature communications 12 (1), 3305, 2021 | 41 | 2021 |
| An engineered IL15 cytokine mutein fused to an anti-PD1 improves intratumoral T-cell function and antitumor immunity Y Xu, LC Carrascosa, YA Yeung, MLH Chu, W Yang, I Djuretic, ... Cancer immunology research 9 (10), 1141-1157, 2021 | 38 | 2021 |
| Biophysical and X-ray Crystallographic Analysis of Mps1 Kinase Inhibitor Complexes, MLH Chu, Z Lang, LMG Chavas, J Neres, OS Fedorova, L Tabernero, ... Biochemistry 49 (8), 1689-1701, 2010 | 35 | 2010 |
| One size does not fit all: navigating the multi-dimensional space to optimize T-cell engaging protein therapeutics W Chen, F Yang, C Wang, J Narula, E Pascua, I Ni, S Ding, X Deng, ... MAbs 13 (1), 1871171, 2021 | 34 | 2021 |
| Fusion core structure of the severe acute respiratory syndrome coronavirus (SARS‐CoV): In search of potent SARS‐CoV entry inhibitors LHM Chu, SH Chan, SN Tsai, Y Wang, CHK Cheng, KB Wong, ... Journal of cellular biochemistry 104 (6), 2335-2347, 2008 | 29 | 2008 |
| Ligand-blocking and membrane-proximal domain targeting anti-OX40 antibodies mediate potent T cell-stimulatory and anti-tumor activity P Zhang, GH Tu, J Wei, P Santiago, LR Larrabee, S Liao-Chan, T Mistry, ... Cell Reports 27 (11), 3117-3123. e5, 2019 | 19 | 2019 |
| Rapid peptide‐based screening on the substrate specificity of severe acute respiratory syndrome (SARS) coronavirus 3C‐like protease by matrix‐assisted laser desorption … LHM Chu, WY Choy, SN Tsai, Z Rao, SM Ngai Protein science 15 (4), 699-709, 2006 | 15 | 2006 |
| The Lick Observatory Supernova Search follow-up program: photometry data release of 70 SESNe WK Zheng, BE Stahl, T De Jaeger, AV Filippenko, SQ Wang, WP Gan, ... Monthly Notices of the Royal Astronomical Society 512 (3), 3195-3214, 2022 | 11 | 2022 |
| An engineered IL15 cytokine mutein fused to an anti-PD1 improves intratumoral T-cell function and antitumor immunity. Cancer Immunol. Res. 2021; 9: 1141–1157. doi: 10.1158/2326 … Y Xu, LC Carrascosa, YA Yeung, ML Chu, W Yang, I Djuretic, DC Pappas, ... CIR-21-0058.[Abstract][CrossRef][Google Scholar], 0 | 7 | |
| Structural insights into metabotropic glutamate receptor activation A Koehl, H Hu, D Feng, B Sun, Y Zhang, MJ Robertson, M Chu, ... Nature 566 (7742), 79, 2019 | 2 | 2019 |
