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Ashwin Unnikrishnan
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Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer
YS Ju, LB Alexandrov, M Gerstung, I Martincorena, S Nik-Zainal, ...
elife 3, e02935, 2014
3842014
Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo
PS Woll, U Kjällquist, O Chowdhury, H Doolittle, DC Wedge, S Thongjuea, ...
Cancer cell 25 (6), 794-808, 2014
3492014
Dynamic changes in histone acetylation regulate origins of DNA replication
A Unnikrishnan, PR Gafken, T Tsukiyama
Nature structural & molecular biology 17 (4), 430-437, 2010
2262010
Genome-wide analysis of transcriptional regulators in human HSPCs reveals a densely interconnected network of coding and noncoding genes
D Beck, JAI Thoms, D Perera, J Schütte, A Unnikrishnan, K Knezevic, ...
Blood, The Journal of the American Society of Hematology 122 (14), e12-e22, 2013
1512013
Integrative genomics identifies the molecular basis of resistance to azacitidine therapy in myelodysplastic syndromes
A Unnikrishnan, E Papaemmanuil, D Beck, NP Deshpande, A Verma, ...
Cell reports 20 (3), 572-585, 2017
1182017
The RNA Atlas expands the catalog of human non-coding RNAs
L Lorenzi, HS Chiu, F Avila Cobos, S Gross, PJ Volders, R Cannoodt, ...
Nature biotechnology 39 (11), 1453-1465, 2021
96*2021
Functional mutations form at CTCF-cohesin binding sites in melanoma due to uneven nucleotide excision repair across the motif
RC Poulos, JAI Thoms, YF Guan, A Unnikrishnan, JE Pimanda, ...
Cell reports 17 (11), 2865-2872, 2016
782016
Human endogenous retroviruses form a reservoir of T cell targets in hematological cancers
SK Saini, AD Ørskov, AM Bjerregaard, A Unnikrishnan, ...
Nature communications 11 (1), 5660, 2020
602020
PDGF-AB and 5-Azacytidine induce conversion of somatic cells into tissue-regenerative multipotent stem cells
V Chandrakanthan, A Yeola, JC Kwan, RA Oliver, Q Qiao, YC Kang, ...
Proceedings of the National Academy of Sciences 113 (16), E2306-E2315, 2016
562016
Srsf2 P95H initiates myeloid bias and myelodysplastic/myeloproliferative syndrome from hemopoietic stem cells
MF Smeets, SY Tan, JJ Xu, G Anande, A Unnikrishnan, AM Chalk, ...
Blood, The Journal of the American Society of Hematology 132 (6), 608-621, 2018
482018
RNA splicing alterations induce a cellular stress response associated with poor prognosis in acute myeloid leukemia
G Anande, NP Deshpande, S Mareschal, AMN Batcha, HR Hampton, ...
Clinical Cancer Research 26 (14), 3597-3607, 2020
322020
AZA-MS: a novel multiparameter mass spectrometry method to determine the intracellular dynamics of azacitidine therapy in vivo
A Unnikrishnan, ANQ Vo, R Pickford, MJ Raftery, AC Nunez, A Verma, ...
Leukemia 32 (4), 900-910, 2018
282018
Overexpression of ERG in cord blood progenitors promotes expansion and recapitulates molecular signatures of high ERG leukemias
ML Tursky, D Beck, JAI Thoms, Y Huang, A Kumari, A Unnikrishnan, ...
Leukemia 29 (4), 819-827, 2015
272015
Demethylation and up-regulation of an oncogene after hypomethylating therapy
YC Liu, J Kwon, E Fabiani, Z Xiao, YV Liu, MY Follo, J Liu, H Huang, ...
New England Journal of Medicine 386 (21), 1998-2010, 2022
262022
Anticancer therapeutic effect of cerium-based nanoparticles: Known and unknown molecular mechanisms
MJN Amaldoss, R Mehmood, JL Yang, P Koshy, N Kumar, ...
Biomaterials Science 10 (14), 3671-3694, 2022
212022
Constitutive CHK1 Expression Drives a pSTAT3–CIP2A Circuit that Promotes Glioblastoma Cell Survival and Growth
A Khanna, JAI Thoms, BW Stringer, SA Chung, KS Ensbey, TR Jue, ...
Molecular Cancer Research 18 (5), 709-722, 2020
212020
HMGA2 promotes long-term engraftment and myeloerythroid differentiation of human hematopoietic stem and progenitor cells
P Kumar, D Beck, R Galeev, JAI Thoms, MS Talkhoncheh, I de Jong, ...
Blood Advances 3 (4), 681-691, 2019
202019
A quantitative proteomics approach identifies ETV6 and IKZF1 as new regulators of an ERG-driven transcriptional network
A Unnikrishnan, YF Guan, Y Huang, D Beck, JAI Thoms, S Peirs, ...
Nucleic acids research 44 (22), 10644-10661, 2016
192016
An Efficient Purification System for Native Minichromosome from Saccharomyces cerevisiae.
A Unnikrishnan, B Akiyoshi, S Biggins, T Tsukiyama
Methods in molecular biology (Clifton, NJ) 833, 115, 2012
182012
Inorganic nanoparticle-based advanced cancer therapies: Promising combination strategies
MJN Amaldoss, JL Yang, P Koshy, A Unnikrishnan, CC Sorrell
Drug Discovery Today, 103386, 2022
162022
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