Ambra Grolla
Ambra Grolla
Associated Professor, UPO
Verified email at
Cited by
Cited by
Amyloid beta deregulates astroglial mGluR5‐mediated calcium signaling via calcineurin and Nf‐kB
D Lim, A Iyer, V Ronco, AA Grolla, PL Canonico, E Aronica, AA Genazzani
Glia 61 (7), 1134-1145, 2013
WIN55212-2 attenuates amyloid-beta-induced neuroinflammation in rats through activation of cannabinoid receptors and PPAR-γ pathway
G Fakhfouri, A Ahmadiani, R Rahimian, AA Grolla, F Moradi, A Haeri
Neuropharmacology 63 (4), 653-666, 2012
Extracellular nicotinamide phosphoribosyltransferase, a new cancer metabokine
AA Grolla, C Travelli, AA Genazzani, JK Sethi
British journal of pharmacology 173 (14), 2182-2194, 2016
Characterization of NAD uptake in mammalian cells
RA Billington, C Travelli, E Ercolano, U Galli, CB Roman, AA Grolla, ...
Journal of Biological Chemistry 283 (10), 6367-6374, 2008
Amyloid-β and Alzheimer’s disease type pathology differentially affects the calcium signalling toolkit in astrocytes from different brain regions
AA Grolla, JA Sim, D Lim, JJ Rodriguez, AA Genazzani, A Verkhratsky
Cell death & disease 4 (5), e623-e623, 2013
Recent advances in NAMPT inhibitors: a novel immunotherapic strategy
U Galli, G Colombo, C Travelli, GC Tron, AA Genazzani, AA Grolla
Frontiers in pharmacology 11, 531540, 2020
Aβ leads to Ca2+ signaling alterations and transcriptional changes in glial cells
AA Grolla, G Fakhfouri, G Balzaretti, E Marcello, F Gardoni, PL Canonico, ...
Neurobiology of aging 34 (2), 511-522, 2013
Differential deregulation of astrocytic calcium signalling by amyloid-β, TNFα, IL-1β and LPS
V Ronco, AA Grolla, TN Glasnov, PL Canonico, A Verkhratsky, ...
Cell Calcium 55 (4), 219-229, 2014
Glial calcium signalling in Alzheimer’s disease
D Lim, V Ronco, AA Grolla, A Verkhratsky, AA Genazzani
Reviews of Physiology, Biochemistry and Pharmacology, Vol. 167, 45-65, 2014
Nicotinamide phosphoribosyltransferase acts as a metabolic gate for mobilization of myeloid-derived suppressor cells
C Travelli, FM Consonni, S Sangaletti, M Storto, S Morlacchi, AA Grolla, ...
Cancer research 79 (8), 1938-1951, 2019
Differentiation of adipose-derived stem cells into Schwann cell phenotype induces expression of P2X receptors that control cell death
A Faroni, SW Rothwell, AA Grolla, G Terenghi, V Magnaghi, A Verkhratsky
Cell death & disease 4 (7), e743-e743, 2013
Nicotinamide phosphoribosyltransferase (NAMPT/PBEF/visfatin) is a tumoural cytokine released from melanoma
AA Grolla, S Torretta, I Gnemmi, A Amoruso, G Orsomando, M Gatti, ...
Pigment cell & melanoma research 28 (6), 718-729, 2015
Identification of novel triazole-based nicotinamide phosphoribosyltransferase (NAMPT) inhibitors endowed with antiproliferative and antiinflammatory activity
C Travelli, S Aprile, R Rahimian, AA Grolla, F Rogati, M Bertolotti, ...
Journal of medicinal chemistry 60 (5), 1768-1792, 2017
Synthesis, biological evaluation, and molecular docking of Ugi products containing a zinc-chelating moiety as novel inhibitors of histone deacetylases
AA Grolla, V Podesta, MG Chini, S Di Micco, A Vallario, AA Genazzani, ...
Journal of medicinal chemistry 52 (9), 2776-2785, 2009
Neutralization of extracellular NAMPT (nicotinamide phosphoribosyltransferase) ameliorates experimental murine colitis
G Colombo, N Clemente, A Zito, C Bracci, FS Colombo, S Sangaletti, ...
Journal of Molecular Medicine 98, 595-612, 2020
Synthesis, molecular docking and biological evaluation as HDAC inhibitors of cyclopeptide mimetics by a tandem three-component reaction and intramolecular [3+ 2] cycloaddition
T Pirali, V Faccio, R Mossetti, AA Grolla, S Di Micco, G Bifulco, ...
Molecular diversity 14, 109-121, 2010
Triazole-curcuminoids: a new class of derivatives for ‘tuning’curcumin bioactivities?
D Caprioglio, S Torretta, M Ferrari, C Travelli, AA Grolla, F Condorelli, ...
Bioorganic & Medicinal Chemistry 24 (2), 140-152, 2016
OXER1 and RACK1-associated pathway: A promising drug target for breast cancer progression
M Masi, E Garattini, M Bolis, D Di Marino, L Maraccani, E Morelli, ...
Oncogenesis 9 (12), 105, 2020
A nicotinamide phosphoribosyltransferase–GAPDH interaction sustains the stress-induced NMN/NAD+ salvage pathway in the nucleus
AA Grolla, R Miggiano, D Di Marino, M Bianchi, A Gori, G Orsomando, ...
Journal of Biological Chemistry 295 (11), 3635-3651, 2020
The cytokine nicotinamide phosphoribosyltransferase (eNAMPT; PBEF; visfatin) acts as a natural antagonist of CC chemokine receptor type 5 (CCR5)
S Torretta, G Colombo, C Travelli, S Boumya, D Lim, AA Genazzani, ...
Cells 9 (2), 496, 2020
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