| NLRP3 inflammasome activation results in hepatocyte pyroptosis, liver inflammation, and fibrosis in mice A Wree, A Eguchi, MD McGeough, CA Pena, CD Johnson, A Canbay, ... Hepatology 59 (3), 898-910, 2014 | 890 | 2014 |
| Protein transduction domain of HIV-1 Tat protein promotes efficient delivery of DNA into mammalian cells A Eguchi, T Akuta, H Okuyama, T Senda, H Yokoi, H Inokuchi, S Fujita, ... Journal of Biological Chemistry 276 (28), 26204-26210, 2001 | 427 | 2001 |
| Efficient siRNA delivery into primary cells by a peptide transduction domain–dsRNA binding domain fusion protein A Eguchi, BR Meade, YC Chang, CT Fredrickson, K Willert, N Puri, ... Nature biotechnology 27 (6), 567-571, 2009 | 410 | 2009 |
| Hepatocyte pyroptosis and release of inflammasome particles induce stellate cell activation and liver fibrosis S Gaul, A Leszczynska, F Alegre, B Kaufmann, CD Johnson, LA Adams, ... Journal of hepatology 74 (1), 156-167, 2021 | 332 | 2021 |
| Circulating extracellular vesicles with specific proteome and liver microRNAs are potential biomarkers for liver injury in experimental fatty liver disease D Povero, A Eguchi, H Li, CD Johnson, BG Papouchado, A Wree, ... PloS one 9 (12), e113651, 2014 | 282 | 2014 |
| Biomarkers of liver cell death A Eguchi, A Wree, AE Feldstein Journal of hepatology 60 (5), 1063-1074, 2014 | 242 | 2014 |
| NLRP3 inflammasome driven liver injury and fibrosis: roles of IL‐17 and TNF in mice A Wree, MD McGeough, ME Inzaugarat, A Eguchi, S Schuster, ... Hepatology 67 (2), 736-749, 2018 | 237 | 2018 |
| Lipid-induced toxicity stimulates hepatocytes to release angiogenic microparticles that require Vanin-1 for uptake by endothelial cells D Povero, A Eguchi, IR Niesman, N Andronikou, X de Mollerat du Jeu, ... Science signaling 6 (296), ra88-ra88, 2013 | 224 | 2013 |
| Efficient delivery of RNAi prodrugs containing reversible charge-neutralizing phosphotriester backbone modifications BR Meade, K Gogoi, AS Hamil, C Palm-Apergi, A Berg, JC Hagopian, ... Nature biotechnology 32 (12), 1256-1261, 2014 | 213 | 2014 |
| Lipid-induced hepatocyte-derived extracellular vesicles regulate hepatic stellate cells via microRNA targeting peroxisome proliferator-activated receptor-γ D Povero, N Panera, A Eguchi, CD Johnson, BG Papouchado, ... Cellular and molecular gastroenterology and hepatology 1 (6), 646-663. e4, 2015 | 205 | 2015 |
| Circulating adipocyte-derived extracellular vesicles are novel markers of metabolic stress A Eguchi, M Lazic, AM Armando, SA Phillips, R Katebian, S Maraka, ... Journal of molecular medicine 94, 1241-1253, 2016 | 147 | 2016 |
| siRNA delivery using peptide transduction domains A Eguchi, SF Dowdy Trends in pharmacological sciences 30 (7), 341-345, 2009 | 134 | 2009 |
| Extracellular vesicles released by hepatocytes from gastric infusion model of alcoholic liver disease contain a MicroRNA barcode that can be detected in blood A Eguchi, RG Lazaro, J Wang, J Kim, D Povero, B Willliams, SB Ho, ... Hepatology 65 (2), 475-490, 2017 | 104 | 2017 |
| Microparticles release by adipocytes act as “find-me” signals to promote macrophage migration A Eguchi, A Mulya, M Lazic, D Radhakrishnan, MP Berk, D Povero, ... PloS one 10 (4), e0123110, 2015 | 103 | 2015 |
| Circulating microRNAs: emerging biomarkers of liver disease M Arrese, A Eguchi, AE Feldstein Seminars in liver disease 35 (01), 043-054, 2015 | 96 | 2015 |
| Induction of in vivo synthetic lethal RNAi responses to treat glioblastoma H Michiue, A Eguchi, M Scadeng, SF Dowdy Cancer biology & therapy 8 (23), 2304-2311, 2009 | 94 | 2009 |
| Human induced pluripotent stem cell–derived extracellular vesicles reduce hepatic stellate cell activation and liver fibrosis D Povero, EM Pinatel, A Leszczynska, NP Goyal, T Nishio, J Kim, ... JCI insight 4 (14), 2019 | 93 | 2019 |
| Arginase 2 deficiency results in spontaneous steatohepatitis: a novel link between innate immune activation and hepatic de novo lipogenesis LA Navarro, A Wree, D Povero, MP Berk, A Eguchi, S Ghosh, ... Journal of hepatology 62 (2), 412-420, 2015 | 86 | 2015 |
| Differential activation of hepatic invariant NKT cell subsets plays a key role in progression of nonalcoholic steatohepatitis I Maricic, I Marrero, A Eguchi, R Nakamura, CD Johnson, S Dasgupta, ... The Journal of Immunology 201 (10), 3017-3035, 2018 | 82 | 2018 |
| Oxidized linoleic acid metabolites induce liver mitochondrial dysfunction, apoptosis, and NLRP3 activation in mice S Schuster, CD Johnson, M Hennebelle, T Holtmann, AY Taha, IA Kirpich, ... Journal of lipid research 59 (9), 1597-1609, 2018 | 78 | 2018 |
