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Hugo Ceulemans
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Year
Functional diversity of protein phosphatase-1, a cellular economizer and reset button
H Ceulemans, M Bollen
Physiological reviews 84 (1), 1-39, 2004
8062004
Structure-based assembly of protein complexes in yeast
P Aloy, B Bottcher, H Ceulemans, C Leutwein, C Mellwig, S Fischer, ...
Science 303 (5666), 2026-2029, 2004
4322004
The relationship between sequence and interaction divergence in proteins
P Aloy, H Ceulemans, A Stark, RB Russell
Journal of molecular biology 332 (5), 989-998, 2003
3712003
Nucleotide pyrophosphatases/phosphodiesterases on the move
M Bollen, R Gijsbers, H Ceulemans, W Stalmans, C Stefan
Critical reviews in biochemistry and molecular biology 35 (6), 393-432, 2000
3442000
Large-scale comparison of machine learning methods for drug target prediction on ChEMBL
A Mayr, G Klambauer, T Unterthiner, M Steijaert, JK Wegner, ...
Chemical science 9 (24), 5441-5451, 2018
3332018
Docking motif-guided mapping of the interactome of protein phosphatase-1
A Hendrickx, M Beullens, H Ceulemans, T Den Abt, A Van Eynde, ...
Chemistry & biology 16 (4), 365-371, 2009
3222009
Degeneracy and function of the ubiquitous RVXF motif that mediates binding to protein phosphatase-1
P Wakula, M Beullens, H Ceulemans, W Stalmans, M Bollen
Journal of Biological Chemistry 278 (21), 18817-18823, 2003
2412003
Regulator‐driven functional diversification of protein phosphatase‐1 in eukaryotic evolution
H Ceulemans, W Stalmans, M Bollen
Bioessays 24 (4), 371-381, 2002
2112002
Structural and catalytic similarities between nucleotide pyrophosphatases/phosphodiesterases and alkaline phosphatases
R Gijsbers, H Ceulemans, W Stalmans, M Bollen
Journal of Biological Chemistry 276 (2), 1361-1368, 2001
2082001
Deep learning as an opportunity in virtual screening
T Unterthiner, A Mayr, G Klambauer, M Steijaert, JK Wegner, ...
Proceedings of the deep learning workshop at NIPS 27, 1-9, 2014
1952014
Repurposing high-throughput image assays enables biological activity prediction for drug discovery
J Simm, G Klambauer, A Arany, M Steijaert, JK Wegner, E Gustin, ...
Cell chemical biology 25 (5), 611-618. e3, 2018
1592018
Virology analyses of HCV isolates from genotype 1-infected patients treated with simeprevir plus peginterferon/ribavirin in Phase IIb/III studies
O Lenz, T Verbinnen, B Fevery, L Tambuyzer, L Vijgen, M Peeters, ...
Journal of hepatology 62 (5), 1008-1014, 2015
1582015
ExCAPE-DB: an integrated large scale dataset facilitating Big Data analysis in chemogenomics
J Sun, N Jeliazkova, V Chupakhin, JF Golib-Dzib, O Engkvist, L Carlsson, ...
Journal of cheminformatics 9 (1), 1-9, 2017
1282017
Human UBN1 is an ortholog of yeast Hpc2p and has an essential role in the HIRA/ASF1a chromatin-remodeling pathway in senescent cells
G Banumathy, N Somaiah, R Zhang, Y Tang, J Hoffmann, M Andrake, ...
Molecular and cellular biology 29 (3), 758-770, 2009
1222009
Geminate Structures of African Cassava Mosaic Virus
B Böttcher, S Unseld, H Ceulemans, RB Russell, H Jeske
Journal of virology 78 (13), 6758-6765, 2004
1222004
Image-based profiling for drug discovery: due for a machine-learning upgrade?
SN Chandrasekaran, H Ceulemans, JD Boyd, AE Carpenter
Nature Reviews Drug Discovery 20 (2), 145-159, 2021
1112021
A yeast exosome cofactor, Mpp6, functions in RNA surveillance and in the degradation of noncoding RNA transcripts
L Milligan, L Decourty, C Saveanu, J Rappsilber, H Ceulemans, ...
Molecular and cellular biology 28 (17), 5446-5457, 2008
1012008
Substrate specificity and activity regulation of protein kinase MELK
M Beullens, S Vancauwenbergh, N Morrice, R Derua, H Ceulemans, ...
Journal of Biological Chemistry 280 (48), 40003-40011, 2005
1002005
High‐parameter mass cytometry evaluation of relapsed/refractory multiple myeloma patients treated with daratumumab demonstrates immune modulation as a novel mechanism of action
HC Adams III, F Stevenaert, J Krejcik, K Van der Borght, T Smets, J Bald, ...
Cytometry Part A 95 (3), 279-289, 2019
962019
Structural basis for the high Ca2+ affinity of the ubiquitous SERCA2b Ca2+ pump
I Vandecaetsbeek, M Trekels, M De Maeyer, H Ceulemans, E Lescrinier, ...
Proceedings of the National Academy of Sciences 106 (44), 18533-18538, 2009
882009
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Articles 1–20