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Lauren G. Friedman
Lauren G. Friedman
Cambrian BioPharma
Adresă de e-mail confirmată pe cambrianbio.com
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Disrupted autophagy leads to dopaminergic axon and dendrite degeneration and promotes presynaptic accumulation of α-synuclein and LRRK2 in the brain
LG Friedman, ML Lachenmayer, J Wang, L He, SM Poulose, M Komatsu, ...
Journal of Neuroscience 32 (22), 7585-7593, 2012
3162012
The cellular pathways of neuronal autophagy and their implication in neurodegenerative diseases
Z Yue, L Friedman, M Komatsu, K Tanaka
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1793 (9), 1496-1507, 2009
2122009
Promoting autophagic clearance: viable therapeutic targets in Alzheimer's disease
LG Friedman, YH Qureshi, WH Yu
Neurotherapeutics 12 (1), 94-108, 2015
992015
Wdr5, a WD-40 protein, regulates osteoblast differentiation during embryonic bone development
F Gori, LG Friedman, MB Demay
Developmental biology 295 (2), 498-506, 2006
602006
Potential application of grape derived polyphenols in Huntington’s disease
J Wang, CM Pfleger, L Friedman, R Vittorino, W Zhao, X Qian, L Conley, ...
Translational neuroscience 1, 95-100, 2010
452010
Cadherin-based transsynaptic networks in establishing and modifying neural connectivity
LG Friedman, DL Benson, GW Huntley
Current topics in developmental biology 112, 415-465, 2015
422015
Cadherin‐8 expression, synaptic localization, and molecular control of neuronal form in prefrontal corticostriatal circuits
LG Friedman, FW Riemslagh, JM Sullivan, R Mesias, FM Williams, ...
Journal of Comparative Neurology 523 (1), 75-92, 2015
342015
Value-generating exploratory trials in neurodegenerative dementias
LG Friedman, N McKeehan, Y Hara, JL Cummings, DC Matthews, J Zhu, ...
Neurology 96 (20), 944-954, 2021
222021
Guidelines to improve animal study design and reproducibility for Alzheimer's disease and related dementias: For funders and researchers
HM Snyder, DW Shineman, LG Friedman, JA Hendrix, A Khachaturian, ...
Alzheimer's & Dementia 12 (11), 1177-1185, 2016
212016
Wdr5, a novel WD repeat protein, regulates osteoblast and chondrocyte differentiation in vivo
F Gori, L Friedman, MB Demay
JOURNAL OF MUSCULOSKELETAL AND NEURONAL INTERACTIONS 5 (4), 338, 2005
212005
Grape-seed polyphenolic extract improves the eye phenotype in a Drosophila model of tauopathy
CM Pfleger, J Wang, L Friedman, R Vittorino, LM Conley, L Ho, ...
International Journal of Alzheimer’s Disease 2010, 2010
112010
Meeting report on the Alzheimer’s drug discovery foundation 14th international conference on Alzheimer’s drug discovery
LG Friedman, K Price, RF Lane, AJ Carman, PA Dacks, DW Shineman, ...
Alzheimer's Research & Therapy 6, 1-4, 2014
72014
Optimizing the use of CROs by academia and small companies
RF Lane, LG Friedman, C Keith, SP Braithwaite, JA Frearson, DA Lowe, ...
Nature reviews Drug discovery 12 (7), 487-488, 2013
72013
Commentary: Global Alzheimer's disease and Alzheimer's disease related dementia research funding organizations support and engage the research community throughout the COVID‐19 …
EA Meyers, P Amouyel, DE Bovenkamp, MC Carrillo, GD De Buchy, ...
Alzheimer's & Dementia 18 (5), 1067-1070, 2022
42022
Development and cadherin-mediated control of prefrontal corticostriatal projections in mice
RE Mesías, Y Zaki, CA Guevara, LG Friedman, A Hussein, K Therrien, ...
Iscience 26 (10), 2023
2023
Development of prefrontal corticostriatal connectivity in mice
RE Mesías, Y Zaki, CA Guevara, LG Friedman, A Hussein, K Therrien, ...
bioRxiv, 2023.03. 14.532475, 2023
2023
Valley of Death and the Role of Venture Philanthropy in Alzheimer’s Disease Drug Development
LG Friedman, M Owen, A Travaglia, H Fillit
Alzheimer's Disease Drug Development: Research and Development Ecosystem, 480, 2022
2022
Molecular Mechanisms Underlying Striatal Circuitry in Development and Degeneration
LG Friedman
Icahn School of Medicine at Mount Sinai, 2014
2014
AUTOPHAGY IN HUNTINGTON’S AND PARKINSON’S DISEASES: PATHOGENIC MECHANISMS AND THERAPEUTIC POTENTIALS
J Lim, LG Friedman, NC McKnight, Z Yue
Autophagy of the Nervous System: Cellular Self-Digestion in Neurons and …, 2012
2012
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Articole 1–19