| Acidic stress promotes a glioma stem cell phenotype AB Hjelmeland, Q Wu, JM Heddleston, GS Choudhary, J MacSwords, ... Cell Death & Differentiation 18 (5), 829-840, 2011 | 458 | 2011 |
| MCL-1 and BCL-xL-dependent resistance to the BCL-2 inhibitor ABT-199 can be overcome by preventing PI3K/AKT/mTOR activation in lymphoid malignancies GS Choudhary, S Al-Harbi, S Mazumder, BT Hill, MR Smith, J Bodo, ... Cell death & disease 6 (1), e1593-e1593, 2015 | 364 | 2015 |
| Caspase-3 activation is a critical determinant of genotoxic stress-induced apoptosis GS Choudhary, S Al-Harbi, A Almasan Apoptosis and Cancer: Methods and Protocols, 1-9, 2015 | 294 | 2015 |
| U2AF1 mutations induce oncogenic IRAK4 isoforms and activate innate immune pathways in myeloid malignancies MA Smith, GS Choudhary, A Pellagatti, K Choi, LC Bolanos, TD Bhagat, ... Nature cell biology 21 (5), 640-650, 2019 | 186 | 2019 |
| Direct activation of BAX by BTSA1 overcomes apoptosis resistance in acute myeloid leukemia DE Reyna, TP Garner, A Lopez, F Kopp, GS Choudhary, A Sridharan, ... Cancer cell 32 (4), 490-505. e10, 2017 | 152 | 2017 |
| Pyrogallol and its analogs can antagonize bacterial quorum sensing in Vibrio harveyi N Ni, G Choudhary, M Li, B Wang Bioorganic & medicinal chemistry letters 18 (5), 1567-1572, 2008 | 128 | 2008 |
| PARP inhibition sensitizes to low dose-rate radiation TMPRSS2-ERG fusion gene-expressing and PTEN-deficient prostate cancer cells P Chatterjee, GS Choudhary, A Sharma, K Singh, WD Heston, J Ciezki, ... PloS one 8 (4), e60408, 2013 | 127 | 2013 |
| Mcl-1 Phosphorylation defines ABT-737 resistance that can be overcome by increased NOXA expression in leukemic B cells S Mazumder, GS Choudhary, S Al-Harbi, A Almasan Cancer research 72 (12), 3069-3079, 2012 | 123 | 2012 |
| Lactate-mediated epigenetic reprogramming regulates formation of human pancreatic cancer-associated fibroblasts TD Bhagat, D Von Ahrens, M Dawlaty, Y Zou, J Baddour, A Achreja, ... Elife 8, e50663, 2019 | 116 | 2019 |
| An antiapoptotic BCL-2 family expression index predicts the response of chronic lymphocytic leukemia to ABT-737 S Al-Harbi, BT Hill, S Mazumder, K Singh, J DeVecchio, G Choudhary, ... Blood, The Journal of the American Society of Hematology 118 (13), 3579-3590, 2011 | 116 | 2011 |
| Efficacy of booster doses in augmenting waning immune responses to COVID-19 vaccine in patients with cancer LC Shapiro, A Thakkar, ST Campbell, SK Forest, K Pradhan, ... Cancer Cell 40 (1), 3-5, 2022 | 98 | 2022 |
| Upregulation of TET activity with ascorbic acid induces epigenetic modulation of lymphoma cells N Shenoy, T Bhagat, E Nieves, M Stenson, J Lawson, GS Choudhary, ... Blood cancer journal 7 (7), e587-e587, 2017 | 87 | 2017 |
| Antisense STAT3 inhibitor decreases viability of myelodysplastic and leukemic stem cells A Shastri, G Choudhary, M Teixeira, S Gordon-Mitchell, N Ramachandra, ... The Journal of clinical investigation 128 (12), 5479-5488, 2018 | 77 | 2018 |
| Ascorbic acid–induced TET activation mitigates adverse hydroxymethylcytosine loss in renal cell carcinoma N Shenoy, TD Bhagat, J Cheville, C Lohse, S Bhattacharyya, A Tischer, ... The Journal of clinical investigation 129 (4), 1612-1625, 2019 | 75 | 2019 |
| North American ATLL has a distinct mutational and transcriptional profile and responds to epigenetic therapies UA Shah, EY Chung, O Giricz, K Pradhan, K Kataoka, S Gordon-Mitchell, ... Blood, The Journal of the American Society of Hematology 132 (14), 1507-1518, 2018 | 73 | 2018 |
| Epigenetically aberrant stroma in MDS propagates disease via Wnt/β-catenin activation TD Bhagat, S Chen, M Bartenstein, AT Barlowe, D Von Ahrens, ... Cancer research 77 (18), 4846-4857, 2017 | 70 | 2017 |
| Cyclin E/Cdk2-dependent phosphorylation of Mcl-1 determines its stability and cellular sensitivity to BH3 mimetics GS Choudhary, TT Tat, S Misra, BT Hill, MR Smith, A Almasan, ... Oncotarget 6 (19), 16912, 2015 | 68 | 2015 |
| Synthesis and Evaluation of New Antagonists of Bacterial Quorum Sensing in Vibrio harveyi H Peng, Y Cheng, N Ni, M Li, G Choudhary, HT Chou, CD Lu, PC Tai, ... ChemMedChem: Chemistry Enabling Drug Discovery 4 (9), 1457-1468, 2009 | 63 | 2009 |
| Notch pathway is activated via genetic and epigenetic alterations and is a therapeutic target in clear cell renal cancer TD Bhagat, Y Zou, S Huang, J Park, MB Palmer, C Hu, W Li, N Shenoy, ... Journal of Biological Chemistry 292 (3), 837-846, 2017 | 57 | 2017 |
| The TMPRSS2–ERG gene fusion blocks XRCC4-mediated nonhomologous end-joining repair and radiosensitizes prostate cancer cells to PARP inhibition P Chatterjee, GS Choudhary, T Alswillah, X Xiong, WD Heston, ... Molecular cancer therapeutics 14 (8), 1896-1906, 2015 | 52 | 2015 |
