Distinct hypothalamic control of same-and opposite-sex mounting behaviour in mice T Karigo, A Kennedy, B Yang, M Liu, D Tai, IA Wahle, DJ Anderson Nature 589 (7841), 258-263, 2021 | 108 | 2021 |
SGK1 phosphorylation of IκB kinase α and p300 up-regulates NF-κB activity and increases N-methyl-D-aspartate receptor NR2A and NR2B expression DJC Tai, CC Su, YL Ma, EHY Lee Journal of Biological Chemistry 284 (7), 4073-4089, 2009 | 104 | 2009 |
Engineering microdeletions and microduplications by targeting segmental duplications with CRISPR DJC Tai, A Ragavendran, P Manavalan, A Stortchevoi, CM Seabra, ... Nature neuroscience 19 (3), 517-522, 2016 | 84 | 2016 |
MeCP2 SUMOylation rescues Mecp2-mutant-induced behavioural deficits in a mouse model of Rett syndrome DJC Tai, YC Liu, WL Hsu, YL Ma, SJ Cheng, SY Liu, EHY Lee Nature communications 7 (1), 10552, 2016 | 72 | 2016 |
CREB SUMOylation by the E3 ligase PIAS1 enhances spatial memory YC Chen, WL Hsu, YL Ma, DJC Tai, EHY Lee Journal of Neuroscience 34 (29), 9574-9589, 2014 | 57 | 2014 |
Novel role and mechanism of protein inhibitor of activated STAT1 in spatial learning DJC Tai, WL Hsu, YC Liu, YL Ma, EHY Lee The EMBO journal 30 (1), 205-220, 2011 | 48 | 2011 |
Loss of MAGEL2 in Prader-Willi syndrome leads to decreased secretory granule and neuropeptide production H Chen, AK Victor, J Klein, KF Tacer, DJC Tai, C de Esch, A Nuttle, ... JCI insight 5 (17), 2020 | 45 | 2020 |
16p11. 2 deletion is associated with hyperactivation of human iPSC-derived dopaminergic neuron networks and is rescued by RHOA inhibition in vitro M Sundberg, H Pinson, RS Smith, KD Winden, P Venugopal, DJC Tai, ... Nature communications 12 (1), 2897, 2021 | 37 | 2021 |
A novel defense mechanism that is activated on amyloid-β insult to mediate cell survival: role of SGK1-STAT1/STAT2 signaling WL Hsu, TH Chiu, DJC Tai, YL Ma, EHY Lee Cell Death & Differentiation 16 (11), 1515-1529, 2009 | 27 | 2009 |
Restoring Wnt6 signaling ameliorates behavioral deficits in MeCP2 T158A mouse model of Rett syndrome WL Hsu, YL Ma, YC Liu, DJC Tai, EHY Lee Scientific Reports 10 (1), 1074, 2020 | 21 | 2020 |
Tissue-and cell-type-specific molecular and functional signatures of 16p11. 2 reciprocal genomic disorder across mouse brain and human neuronal models DJC Tai, P Razaz, S Erdin, D Gao, J Wang, X Nuttle, CE De Esch, ... The American Journal of Human Genetics 109 (10), 1789-1813, 2022 | 15 | 2022 |
Biallelic mutation of FBXL7 suggests a novel form of Hennekam syndrome PM Boone, S Paterson, K Mohajeri, W Zhu, CA Genetti, DJC Tai, N Nori, ... American Journal of Medical Genetics Part A 182 (1), 189-194, 2020 | 15 | 2020 |
Orgo-Seq integrates single-cell and bulk transcriptomic data to identify cell type specific-driver genes associated with autism spectrum disorder ET Lim, Y Chan, P Dawes, X Guo, S Erdin, DJC Tai, S Liu, JM Reichert, ... Nature Communications 13 (1), 3243, 2022 | 14 | 2022 |
Statistical and functional convergence of common and rare genetic influences on autism at chromosome 16p DJ Weiner, E Ling, S Erdin, DJC Tai, R Yadav, J Grove, JM Fu, A Nadig, ... Nature genetics 54 (11), 1630-1639, 2022 | 13 | 2022 |
Transcriptional and functional consequences of alterations to MEF2C and its topological organization in neuronal models K Mohajeri, R Yadav, E D'haene, PM Boone, S Erdin, D Gao, ... The American Journal of Human Genetics 109 (11), 2049-2067, 2022 | 11 | 2022 |
Transcriptional consequences of MBD5 disruption in mouse brain and CRISPR-derived neurons CM Seabra, T Aneichyk, S Erdin, DJC Tai, CEF De Esch, P Razaz, Y An, ... Molecular autism 11, 1-15, 2020 | 11 | 2020 |
Excitatory dysfunction drives network and calcium handling deficits in 16p11. 2 duplication schizophrenia induced pluripotent stem cell–derived neurons E Parnell, L Culotta, MP Forrest, HA Jalloul, BL Eckman, DD Loizzo, ... Biological psychiatry 94 (2), 153-163, 2023 | 10 | 2023 |
Hardware migration C Leen, AD Halford, RA Kolasa, D Tai, J Meruva US Patent 10,412,849, 2019 | 6 | 2019 |
Identifying cell type specific driver genes in autism-associated copy number loci from cerebral organoids ET Lim, Y Chan, MJ Burns, X Guo, S Erdin, DJC Tai, JM Reichert, ... bioRxiv, 2020.11. 15.375386, 2020 | 5 | 2020 |
Parallelized engineering of mutational models using piggyBac transposon delivery of CRISPR libraries X Nuttle, ND Burt, B Currall, M Moysés-Oliveira, K Mohajeri, R Bhavsar, ... Cell Reports Methods 4 (1), 2024 | 3 | 2024 |